Chronic Hepatitis B And C: Basic Science To Clinical Applications

Chronic Hepatitis B And C: Basic Science To Clinical Applications

Basic Science to Clinical Applications

Chiaho Shih


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The scope of the book is very broad, covering a wide range of areas in HBV/HDV and HCV research, including both basic and clinical science. The selected topics range from epidemiology, immunology, molecular virology and oncology, to clinical therapy.

Chronic Hepatitis B and C consists of 14 chapters, each being a review of a special topic on HBV or HCV. While review articles on a special topic can be found in periodical journals, they tend to be more restricted in presentation. Therefore, this book will provide more in-depth coverage of what are presented as “unpublished results” and “data not shown” in journal articles. Furthermore, several authors in this book do not write review articles regularly. Some authors wrote reviews on a specific topic regularly, but they tried a new topic in this book (e.g., Dr. YF Liaw on “natural course,” Dr. Shih on “virion release,” Dr. Michael Lai on “lymphotropism of HCV,” etc. ⋯). Overall, the book will offer useful information at the cutting age.

  • Hepatitis B Virus:
    • Natural Course of Chronic Hepatitis B Virus Infection (Chia-Ming Chu and Yun-Fan Liaw)
    • Immune Response and Viral Hepatitis B (David R Milich)
    • Epidemiology of Viral Hepatitis B-related Hepatocellular Carcinoma (Katherine A McGlynn, Alison A Evans and W Thomas London)
    • Molecular Biology of HBV-related Hepatocellular Carcinoma (Amanda J Hodgson and Betty L Slagle)
    • Treatment of Chronic Viral Hepatitis B and Drug Resistant Variants (Tin Nguyen, Paul Desmond and Stephen Locarnini)
    • Virion Secretion of Naturally Occurring Core Antigen Variants of Human Hepatitis B Virus (Chiaho Shih)
    • Recent Developments in Hepatitis Delta Virus (Camille Sureau)
  • Hepatitis C Virus:
    • Development of an HCV Cell Culture System (Takanobu Kato and Takaji Wakita)
    • Regulation of Innate Immunity and Interferon Defenses by Hepatitis C Virus (Stacy M Horner and Michael Gale Jr)
    • Expression and Functions of Hepatitis C Virus F Protein (Kamile Yuksek and Jing-hsiung James Ou)
    • Lymphotropism of Hepatitis C Virus (Keigo Machida and Michael M.C. Lai)
    • Host Genetic Factors Control Hepatitis C Virus Infection (Yasuhito Tanaka and Masashi Mizokami)
    • Treatment of Hepatitis C Virus Infection: Past, Present and Future (Chun-Jen Liu and Ding-Shinn Chen)
    • Individualized Therapy for Chronic Hepatitis C (Ming-Lung Yu and Wan-Long Chuang)

Readership: Researchers in virology, infectious diseases and cancer medicine.