Handbook Of Nanobiomedical Research: Fundamentals, Applications And Recent Developments (In 4 Volumes)

Handbook Of Nanobiomedical Research: Fundamentals, Applications And Recent Developments (In 4 Volumes)

Fundamentals, Applications and Recent Developments(In 4 Volumes)Volume 1: Materials for NanomedicineVolume 2: Applications in TherapyVolume 3: Applications in DiagnosticsVolume 4: Biology, Safety and Novel Concepts in Nanomedicine

Vladimir Torchilin


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This book consists of 4 volumes containing about 70 chapters covering all the major aspects of the growing area of nanomedicine. Leading scientists from 15 countries cover all major areas of nanobiomedical research — materials for nanomedicine, application of nanomedicine in therapy of various diseases, use of nanomedicines for diagnostic purposes, technology of nanomedicines, and new trends in nanobiomedical research.

This is the first detailed handbook specifically addressing various aspects of nanobiomedicine. Readers are treated to cutting-edge research and the newest data from leading researchers in this area.

  • Materials for Nanomedicine:
    • Liposomal Nanomedicines (Amr S Abu Lila, Tatsuhiro Ishida and Theresa M Allen)
    • Solid Lipid Nanoparticles for Biomedical Applications (Karsten Mäder)
    • Micellar Nanopreparations for Medicine (Rupa Sawant and Aditi Jhaveri)
    • Nanoemulsions in Medicine (William B Tucker and Sandro Mecozzi)
    • Drug Nanocrystals and Nanosuspensions in Medicine (Leena Peltonen, Jouni Hirvonen and Timo Laaksonen)
    • Polymeric Nanosystems for Integrated Image-Guided Cancer Therapy (Amit Singh, Arun K Iyer and Mansoor M Amiji)
    • Polysaccharide-Based Nanocarriers for Drug Delivery (Carmen Teijeiro, Adam McGlone, Noemi Csaba, Marcos Garcia-Fuentes and María J Alonso)
    • Dendrimers for Biomedical Applications (Lisa M Kaminskas, Victoria M McLeod, Seth A Jones, Ben J Boyd and Christopher J H Porter)
    • Layer-by-Layer Nanopreparations for Medicine — Smart Polyelectrolyte Multilayer Capsules and Coatings (Rawil F Fakhrullin, Gleb B Sukhorukov and Yuri M Lvov)
    • Inorganic Nanopreparations for Nanomedicine (James Ramos and Kaushal Rege)
    • Silica-Based Nanoparticles for Biomedical Imaging and Drug Delivery Applications (Stephanie A Kramer and Wenbin Lin)
    • Carbon Nanotubes in Biomedical Applications (Krunal K Mehta, Elena E Paskaleva, Jonathan S Dordick and Ravi S Kane)
    • Core-Shell Nanoparticles for Biomedical Applications (Mahmoud Elsabahy and Karen L Wooley)
    • Structure–Activity Relationships for Tumor-Targeting Gold Nanoparticles (Erik C Dreaden, Ivan H El-Sayed and Mostafa A El-Sayed)
    • Silver Nanoparticles as Novel Antibacterial and Antiviral Agents (Stefania Galdiero, Annarita Falanga, Marco Cantisani, Avinash Ingle, Massimiliano Galdiero and Mahendra Rai)
    • Magnetic Nanoparticles for Drug Delivery (Rainer Tietze, Harald Unterweger and Christoph Alexiou)
    • Quantum Dots as a Platform Nanomaterial for Biomedical Applications (Eleonora Petryayeva, Roza Bidshahri, Kate Liu, Charles A Haynes, Igor L Medintz, and W Russ Algar)
  • Applications in Therapy:
    • The Application of Nanomedicine to Cardiovascular Diseases (Kevin M Bardon, Olivier Kister and Jason R McCarthy)
    • Nanomedicines for Restenosis Therapy (J E Tengood, I Fishbein, R J Levy and M Chorny)
    • Nanopreparations for Cancer Treatment and Diagnostics (Jayant Khandare, Shashwat Banerjee and Tamara Minko)
    • Nanoparticles in the Gastrointestinal Tract (Abraham Rubinstein)
    • Nanopreparations for Oral Administration (D Hubbard, D J Brayden and H Ghandehari)
    • Nanopreparations for Central Nervous System Diseases (Leyuan Xu and Hu Yang)
    • Nanoparticles for Dermal and Transdermal Delivery: Permeation Pathways and Applications (Marianna Foldvari, Marjan Gharagozloo and Christine Li)
    • Lysosomes and Nanotherapeutics: Diseases, Treatments, and Side Effects (Rachel L Manthe and Silvia Muro)
    • Nanostructured Biomaterials for Inhibiting Cancer Cell Functions (Lijuan Zhang and Thomas J Webster)
    • Nanomedicine in Otorhinolaryngology (Carl Philpott)
    • Nanomedicines for Ocular Administration (Yolanda Diebold)
    • Nano-antibiotics: Nanotechnology in Fighting Against Infectious Diseases (Jessica Kemp, Julius Edson, Young Jik Kwon)
    • Nanoparticles as Adjuvants for Vaccination (Juan M Irache, Ana I Camacho and Carlos Gamazo)
    • Nanopreparations for Gene Delivery (Viola B Morris and Vinod Labhasetwar)
    • Cancer Hyperthermia Using Nanomagnetic Particles and Induction of Immune Responses (Takeshi Kobayashi)
    • Clinical Experience with Liposomal Doxorubicin (Giuseppe Visani and Alessandro Isidori)
    • Clinical Experience with Nanoparticle Albumin Bound (Nab) Paclitaxel (Abraxane®) (Prakash Vishnu and Vivek Roy)
  • Applications in Diagnostics:
    • Nano Advantages in Diagnostic Imaging (William T Phillips and Beth Goins)
    • Superparamagnetic Iron Oxides as Imaging Probes of Metastases and Vulnerable Atherosclerotic Plaques (Mary L Mazzanti and Alexei A Bogdanov, Jr)
    • Nanoparticulate Contrast Agents for CT, SPECT and PET Imaging (Suna Erdogan and Mine Silindir)
    • Nanotargeted Radiopharmaceuticals for Nuclear Imaging and Radiotherapy (Gann Ting, Yun-Long Tseng, Chih-Hsien Chang and Te-Wei Lee)
    • Nanoengineering at the Gas–Liquid Interface: Gas-Filled Microbubbles as Tools for Molecular Imaging and Drug Delivery (Alexander L Klibanov)
    • Nanotechnology for Multimodality Imaging: Applications in Disease Detection and Treatment Guidance (Jinzi Zheng, Raquel De Souza David Jaffray and Christine Allen)
    • Theranostic Nanopreparations for Medicine (Anthony J McGoron)
    • Fluorescent Silica Nanoparticles for Medical Imaging (Jeremy Tharkur, Maria Alejandra Ricaurte and Swadeshmukul Santra)
    • Engineered Gold Nanoparticles as Contrast Agents for Biological Medical Imaging (Anna M Sitarski, Sanjeev Kandpal, Jeremy Grant, Andrew Doolittle, Matthew Newsom and Michael D Mason)
    • Photoluminescent Nanoparticles for Optical Imaging in Biology and Medicine (María Teresa Fernández-Argüelles, Rosario Pereiro, José M Costa-Fernández and Alfredo Sanz-Medel)
    • Metal Particles for Photoacoustic Imaging (Dipanjan Pan)
    • Nanoelectrodes for Biomedical Applications (Haibin Shi and Joanne I Yeh)
    • Nanosensors for Biomedicine (Mary K Balaconis and Heather A Clark)
    • In Vivo Photoacoustic Detection of Circulating Cells and Nanoparticles (Jin-Woo Kim, Ekaterina I Galanzha and Vladimir P Zharov)
    • Raman Micro-Spectroscopy as a Non-Invasive Tool to Follow the Intracellular Fate of Nanoparticles (Tatyana Chernenko, Max Diem and Vladimir Torchilin)
    • Clinical Experience with Nanoparticles in Imaging (Patrick D Sutphin and Mukesh Harisinghani)
  • Biology, Safety and Novel Concepts in Nanomedicine:
    • Biology and Safety:
      • Biological Requirement and Safety Assessment of Nanomedicines (Banu Zolnik, Simona Bancos, Jae Seung Kim and Nakissa Sadrieh)
      • Anatomical and Physicochemical Factors Controlling Nanoparticle Pharmacokinetics (S M Moghimi and Z S Farhangrazi)
      • Immunological Issues with Nanomedicines: Immunogenicity, Hypersensitivity, Accelerated Clearance and Immune Suppression (Janos Szebeni and Wim Jiskoot)
      • Toxicology of Mesoporous Silica Particles and Their Uses in Nanomedicine (Xin Xia, Natalia Kupferschmidt and Alfonso E Garcia-Bennett)
      • Cellular Responses Induced by Nanoparticles (Masanori Horie)
      • Regulatory Aspects of Pharmaceutical Nanopreparations (Gerard M Jensen and Linda Soo Hoo)
      • A Short Course on the Chemistry Manufacturing and Control of Liposome-based Pharmaceutical Products (Simon Eastman and Tom Redelmeier)
      • Preclinical to Clinical Development of Nanomedicines (Sonke Svenson)
    • Novel Concepts in Nanomedicine:
      • Organelle-Targeted Nanocarriers (Alexander Koshkaryev)
      • Bacteriophage-Targeted Nanomedicine and Molecular Imaging (Tao Wang and Radhika Narayanaswamy)
      • Stimuli-Sensitive Nanostructured Systems for Biomedical Applications (Barbara Blanco-Fernandez, Angel Concheiro and Carmen Alvarez-Lorenzo)
      • Biomedical Nanopreparations with Controlled Geometry (Catherine A Fromen, Stuart S Dunn and Joseph M DeSimone)
      • Biomimetic Systems in Nanomedicine (Ana Maria Carmona-Ribeiro)
      • Nanoreactors for Biomedical Applications (Fabian Itel, Ionel Adrian Dinu, Pascal Tanner, Ozana Fischer and Cornelia G Palivan)
      • "Click" Reactions: An Emerging Tool for Biology (Annie Castonguay and Dusica Maysinger)

Readership: Academics, researchers, graduate students and professionals interested in contemporary nanomedicine.
Key Features:
  • Covers the whole field of nanobiomedicine
  • Includes chapters from many leading world renowned scientists
  • Provides cutting-edge data